Why do we do research at CABS?

Although 20-40% of adults with bipolar disorder report onset in childhood, historically there was great debate about the existence of bipolar disorder in youth. Research conducted in the last 20 years provides overwhelming evidence that pediatric bipolar disorder exists, can be reliably diagnosed, and is associated with high rates of relapse into young adulthood. Early-onset bipolar disorder is also associated with increased risk for negative outcomes including substance abuse, legal problems and suicide. Thus, the timely recognition and treatment of early-onset bipolar disorder is critical. However, much remains to be known about the course, effective management, and optimal treatment of the illness.

Many of the CABS faculty lead research studies funded by both federal and private foundations through which we aim to learn more about the phenomenology, causes, course, and best treatments for pediatric bipolar disorder. We disseminate our clinical and research experience through conference presentations and peer-reviewed publications and provide education to national and international students, community clinicians, and consumers. Through our research, it is our ultimate goal to improve the quality of life for young people with bipolar disorder and their families living with bipolar disorder.

To learn more about our research, please visit our study pages listed below:

• BASS – Identifying Risk State Profiles in Adolescents: A Prospective Study of Sleep Disturbance and Suicidal Behavior
• BIOS – Bipolar Offspring Study
• COBY– Course and Outcome of Bipolar Disorders in Youth
• KEY – Early Assessment and Intervention for Adolescents At-Risk for Bipolar Disorder
• LAMS –Longitudinal Assessment of Manic Symptoms in Youth
• MI – Brief Motivation Intervention to Improve Medication Adherence Among Adolescents with Bipolar Disorder
• WAVE – Ways for Adolescents to Validate Emotions: A Therapy Study