COBY (Course and Outcome of Bipolar Youth)

Pittsburgh Site Principal Investigator: Boris Birmaher, MD

Pittsburgh Site Co-Investigators: Tina Goldstein, PhD, Rasim Diler MD

The COBY study is funded by the National Institute of Mental Health (NIMH).

This study is no longer recruiting.

COBY is a 15-year multi-site collaboration between University of Pittsburgh, Brown University and the University of California Los Angeles (UCLA), and represents the largest-ever prospective study of youth diagnosed with bipolar disorder. Since its inception, COBY has assessed and followed over 400 youth ages 6-17 on average every 8 months with comprehensive assessments in many areas including course of mood symptoms, psychosocial and cognitive functioning, and substance use. COBY has been critical in furthering our understanding of this complex illness by validating the diagnosis of bipolar disorder in youth and elucidating the phenomenology, course, outcome, and factors associated with long-term prognosis.